LPN Salary

Odessa vs San Antonio: Licensed Practical Nurse Salary (2026)

Compare licensed practical nurse salaries between Odessa, TX and San Antonio, TX. All figures are 2026 estimates projected from BLS 2025 data.

Odessa, TX
$66,052
$31.75/hr
San Antonio, TX
$65,830
$31.65/hr

Side-by-Side Comparison

MetricOdessa, TXSan Antonio, TX
Median Salary$66,052$65,830
Hourly Rate$31.75$31.65
Entry Level (P10)$48,125$53,188
25th Percentile$57,543$61,380
75th Percentile$68,916$72,468
Top Earner (P90)$78,905$81,770
Total Employed3205,970
Side-by-side bar chart comparing Odessa ($66,052) and San Antonio ($65,830) licensed practical nurse salaries.OdessaSan AntonioMedian Salary$66,052$65,830Entry Level (P10)$48,125$53,188Top Earner (P90)$78,905$81,770US Median $68,071

Verdict

Odessa and San Antonio are closely matched on overall licensed practical nurse compensation, each winning on different metrics.

The salary gap between Odessa and San Antonio is $222 (0.34%). Odessa's median is -2.97% compared to the US national median of $68,071.

Salary Range Comparison

The full salary range (10th to 90th percentile) in Odessa spans $30,780,San Antonio spans $28,582. Odessa has a wider pay range, meaning more potential for high earners but also more variation.

Odessa
P10 (Entry)$48,125
P25$57,543
Median$66,052
P75$68,916
P90 (Top)$78,905
San Antonio
P10 (Entry)$53,188
P25$61,380
Median$65,830
P75$72,468
P90 (Top)$81,770

Cost-of-Living Adjusted Comparison

After cost-of-living adjustment, Odessa ($70,346 effective) pays 1.21% more than San Antonio ($69,503 effective).

Odessa
Nominal: $66,052
CoL Index: 93.896
Adjusted: $70,346
San Antonio
Nominal: $65,830
CoL Index: 94.716
Adjusted: $69,503

Cost-of-living adjustment: salary × (100 / CoL index). Index of 100 = national average.

Which City Is Right for You?

Choose Odessa if…

  • Higher median salary ($66,052/year)
  • Better purchasing power (CoL-adjusted: $70,346)
  • You prefer the Texas area and lifestyle

Choose San Antonio if…

  • Better top-earner potential ($81,770)
  • Larger job market (5,970 employed)
  • You prefer the Texas area and lifestyle

Historical Salary Growth Comparison

Based on BLS OEWS metropolitan area data, licensed practical nurse salaries in Odessa grew 37.2% from 2019 to 2025, compared to 36.6% growth in San Antonio over the same period.

Odessa, TX

+37.2%

$45,540 (2019) → $62,490 (2025)

San Antonio, TX

+36.6%

$45,580 (2019) → $62,280 (2025)

View Full Salary Data

Frequently Asked Questions

Which city pays licensed practical nurses more: Odessa or San Antonio?

Odessa has a higher median licensed practical nurse salary at $66,052/year, compared to San Antonio at $65,830/year — a difference of $222 (0.34%).

What is the hourly rate difference between Odessa and San Antonio?

Odessa licensed practical nurses earn $31.75/hr while San Antonio hygienists earn $31.65/hr (2026 est.).

Should I relocate from Odessa to San Antonio as a licensed practical nurse?

Consider more than just salary when comparing Odessa and San Antonio. Factor in cost of living (CoL-adjusted: Odessa = $70,346, San Antonio = $69,503), job availability (320 vs 5,970 employed), commute, and career growth potential.

What do entry-level licensed practical nurses earn in Odessa vs San Antonio?

Entry-level (10th percentile) licensed practical nurses earn $48,125 in Odessa and $53,188 in San Antonio. The San Antonio area offers higher starting salaries.

Related Comparisons

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Written by Aisha Malik, LPN

Career Analyst

Aisha has 10 years of experience as a licensed practical nurse. She specializes in pediatric nursing. Aisha has worked in various outpatient clinics.

Clinically reviewed by Daniel Thompson, LPNData verified by Maria Gonzalez, LPN

Methodology & Data Source

All salary figures are 2026 projections based on BLS OEWS May 2025 data. A 5.70% CAGR (derived from 6-year national BLS trends) was applied to estimate current compensation. Cost-of-living adjustments use BEA Regional Price Parity data. Actual salaries vary by employer, certifications, and experience.

Data Sources & Methodology

Source: BLS, OEWS , released .

Compiled and verified by Aisha Malik, LPN, a licensed licensed practical nurse with 10+ years of clinical experience. · View source data at BLS.gov