LPN Salary

San Francisco vs Fresno: Licensed Practical Nurse Salary (2026)

Compare licensed practical nurse salaries between San Francisco, CA and Fresno, CA. All figures are 2026 estimates projected from BLS 2025 data.

San Francisco, CA
$99,686
$47.92/hr
Fresno, CA
$79,888
$38.41/hr

Side-by-Side Comparison

MetricSan Francisco, CAFresno, CA
Median Salary$99,686$79,888
Hourly Rate$47.92$38.41
Entry Level (P10)$80,226$65,703
25th Percentile$86,304$69,255
75th Percentile$110,044$83,788
Top Earner (P90)$115,340$99,802
Total Employed8,8002,360
Side-by-side bar chart comparing San Francisco ($99,686) and Fresno ($79,888) licensed practical nurse salaries.San FranciscoFresnoMedian Salary$99,686$79,888Entry Level (P10)$80,226$65,703Top Earner (P90)$115,340$99,802US Median $68,071

Verdict

San Francisco, CA offers better overall compensation for licensed practical nurses, winning 4 out of 4 metrics compared to Fresno.

The salary gap between San Francisco and Fresno is $19,798 (24.78%). San Francisco's median is +46.44% compared to the US national median of $68,071.

Salary Range Comparison

The full salary range (10th to 90th percentile) in San Francisco spans $35,114,Fresno spans $34,099. San Francisco has a wider pay range, meaning more potential for high earners but also more variation.

San Francisco
P10 (Entry)$80,226
P25$86,304
Median$99,686
P75$110,044
P90 (Top)$115,340
Fresno
P10 (Entry)$65,703
P25$69,255
Median$79,888
P75$83,788
P90 (Top)$99,802

Cost-of-Living Adjusted Comparison

After cost-of-living adjustment, San Francisco ($86,224 effective) pays 10.26% more than Fresno ($78,200 effective).

San Francisco
Nominal: $99,686
CoL Index: 115.613
Adjusted: $86,224
Fresno
Nominal: $79,888
CoL Index: 102.158
Adjusted: $78,200

Cost-of-living adjustment: salary × (100 / CoL index). Index of 100 = national average.

Which City Is Right for You?

Choose San Francisco if…

  • Higher median salary ($99,686/year)
  • Better top-earner potential ($115,340)
  • Larger job market (8,800 employed)
  • Better purchasing power (CoL-adjusted: $86,224)
  • You prefer the California area and lifestyle

Choose Fresno if…

  • You prefer the California area and lifestyle

Historical Salary Growth Comparison

Based on BLS OEWS metropolitan area data, licensed practical nurse salaries in San Francisco grew 39.7% from 2019 to 2025, compared to 51.5% growth in Fresno over the same period.

San Francisco, CA

+39.7%

$67,520 (2019) → $94,310 (2025)

Fresno, CA

+51.5%

$49,890 (2019) → $75,580 (2025)

View Full Salary Data

Frequently Asked Questions

Which city pays licensed practical nurses more: San Francisco or Fresno?

San Francisco has a higher median licensed practical nurse salary at $99,686/year, compared to Fresno at $79,888/year — a difference of $19,798 (24.78%).

What is the hourly rate difference between San Francisco and Fresno?

San Francisco licensed practical nurses earn $47.92/hr while Fresno hygienists earn $38.41/hr (2026 est.).

Should I relocate from San Francisco to Fresno as a licensed practical nurse?

Consider more than just salary when comparing San Francisco and Fresno. Factor in cost of living (CoL-adjusted: San Francisco = $86,224, Fresno = $78,200), job availability (8,800 vs 2,360 employed), commute, and career growth potential.

What do entry-level licensed practical nurses earn in San Francisco vs Fresno?

Entry-level (10th percentile) licensed practical nurses earn $80,226 in San Francisco and $65,703 in Fresno. The San Francisco area offers higher starting salaries.

Related Comparisons

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Written by Aisha Malik, LPN

Career Analyst

Aisha has 10 years of experience as a licensed practical nurse. She specializes in pediatric nursing. Aisha has worked in various outpatient clinics.

Clinically reviewed by Daniel Thompson, LPNData verified by Maria Gonzalez, LPN

Methodology & Data Source

All salary figures are 2026 projections based on BLS OEWS May 2025 data. A 5.70% CAGR (derived from 6-year national BLS trends) was applied to estimate current compensation. Cost-of-living adjustments use BEA Regional Price Parity data. Actual salaries vary by employer, certifications, and experience.

Data Sources & Methodology

Source: BLS, OEWS , released .

Compiled and verified by Aisha Malik, LPN, a licensed licensed practical nurse with 10+ years of clinical experience. · View source data at BLS.gov