LPN Salary

San Francisco vs Santa Clarita: Licensed Practical Nurse Salary (2026)

Compare licensed practical nurse salaries between San Francisco, CA and Santa Clarita, CA. All figures are 2026 estimates projected from BLS 2025 data.

San Francisco, CA
$99,686
$47.92/hr
Santa Clarita, CA
$85,327
$41.02/hr

Side-by-Side Comparison

MetricSan Francisco, CASanta Clarita, CA
Median Salary$99,686$85,327
Hourly Rate$47.92$41.02
Entry Level (P10)$80,226$64,934
25th Percentile$86,304$77,588
75th Percentile$110,044$104,168
Top Earner (P90)$115,340$117,035
Total Employed8,80041
Side-by-side bar chart comparing San Francisco ($99,686) and Santa Clarita ($85,327) licensed practical nurse salaries.San FranciscoSanta ClaritaMedian Salary$99,686$85,327Entry Level (P10)$80,226$64,934Top Earner (P90)$115,340$117,035US Median $68,071

Verdict

San Francisco, CA offers better overall compensation for licensed practical nurses, winning 3 out of 4 metrics compared to Santa Clarita.

The salary gap between San Francisco and Santa Clarita is $14,359 (16.83%). San Francisco's median is +46.44% compared to the US national median of $68,071.

Salary Range Comparison

The full salary range (10th to 90th percentile) in San Francisco spans $35,114,Santa Clarita spans $52,101. Santa Clarita has a wider pay range, suggesting more variation in pay between entry-level and experienced licensed practical nurses.

San Francisco
P10 (Entry)$80,226
P25$86,304
Median$99,686
P75$110,044
P90 (Top)$115,340
Santa Clarita
P10 (Entry)$64,934
P25$77,588
Median$85,327
P75$104,168
P90 (Top)$117,035

Cost-of-Living Adjusted Comparison

After cost-of-living adjustment, San Francisco ($86,224 effective) pays 14.29% more than Santa Clarita ($75,444 effective).

San Francisco
Nominal: $99,686
CoL Index: 115.613
Adjusted: $86,224
Santa Clarita
Nominal: $85,327
CoL Index: 113.1
Adjusted: $75,444

Cost-of-living adjustment: salary × (100 / CoL index). Index of 100 = national average.

Which City Is Right for You?

Choose San Francisco if…

  • Higher median salary ($99,686/year)
  • Larger job market (8,800 employed)
  • Better purchasing power (CoL-adjusted: $86,224)
  • You prefer the California area and lifestyle

Choose Santa Clarita if…

  • Better top-earner potential ($117,035)
  • You prefer the California area and lifestyle

Historical Salary Growth Comparison

Based on BLS OEWS metropolitan area data, licensed practical nurse salaries in San Francisco grew 39.7% from 2019 to 2025, compared to -10.4% growth in Santa Clarita over the same period.

San Francisco, CA

+39.7%

$67,520 (2019) → $94,310 (2025)

Santa Clarita, CA

+-10.4%

$90,134 (2024) → $80,726 (2025)

View Full Salary Data

Frequently Asked Questions

Which city pays licensed practical nurses more: San Francisco or Santa Clarita?

San Francisco has a higher median licensed practical nurse salary at $99,686/year, compared to Santa Clarita at $85,327/year — a difference of $14,359 (16.83%).

What is the hourly rate difference between San Francisco and Santa Clarita?

San Francisco licensed practical nurses earn $47.92/hr while Santa Clarita hygienists earn $41.02/hr (2026 est.).

Should I relocate from San Francisco to Santa Clarita as a licensed practical nurse?

Consider more than just salary when comparing San Francisco and Santa Clarita. Factor in cost of living (CoL-adjusted: San Francisco = $86,224, Santa Clarita = $75,444), job availability (8,800 vs 41 employed), commute, and career growth potential.

What do entry-level licensed practical nurses earn in San Francisco vs Santa Clarita?

Entry-level (10th percentile) licensed practical nurses earn $80,226 in San Francisco and $64,934 in Santa Clarita. The San Francisco area offers higher starting salaries.

Related Comparisons

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Written by Aisha Malik, LPN

Career Analyst

Aisha has 10 years of experience as a licensed practical nurse. She specializes in pediatric nursing. Aisha has worked in various outpatient clinics.

Clinically reviewed by Daniel Thompson, LPNData verified by Maria Gonzalez, LPN

Methodology & Data Source

All salary figures are 2026 projections based on BLS OEWS May 2025 data. A 5.70% CAGR (derived from 6-year national BLS trends) was applied to estimate current compensation. Cost-of-living adjustments use BEA Regional Price Parity data. Actual salaries vary by employer, certifications, and experience.

Data Sources & Methodology

Source: BLS, OEWS , released .

Compiled and verified by Aisha Malik, LPN, a licensed licensed practical nurse with 10+ years of clinical experience. · View source data at BLS.gov