LPN Salary

San Francisco vs Santa Maria: Licensed Practical Nurse Salary (2026)

Compare licensed practical nurse salaries between San Francisco, CA and Santa Maria, CA. All figures are 2026 estimates projected from BLS 2025 data.

San Francisco, CA
$99,686
$47.92/hr
Santa Maria, CA
$83,514
$40.16/hr

Side-by-Side Comparison

MetricSan Francisco, CASanta Maria, CA
Median Salary$99,686$83,514
Hourly Rate$47.92$40.16
Entry Level (P10)$80,226$69,138
25th Percentile$86,304$80,871
75th Percentile$110,044$89,348
Top Earner (P90)$115,340$101,102
Total Employed8,800650
Side-by-side bar chart comparing San Francisco ($99,686) and Santa Maria ($83,514) licensed practical nurse salaries.San FranciscoSanta MariaMedian Salary$99,686$83,514Entry Level (P10)$80,226$69,138Top Earner (P90)$115,340$101,102US Median $68,071

Verdict

San Francisco, CA offers better overall compensation for licensed practical nurses, winning 4 out of 4 metrics compared to Santa Maria.

The salary gap between San Francisco and Santa Maria is $16,172 (19.36%). San Francisco's median is +46.44% compared to the US national median of $68,071.

Salary Range Comparison

The full salary range (10th to 90th percentile) in San Francisco spans $35,114,Santa Maria spans $31,964. San Francisco has a wider pay range, meaning more potential for high earners but also more variation.

San Francisco
P10 (Entry)$80,226
P25$86,304
Median$99,686
P75$110,044
P90 (Top)$115,340
Santa Maria
P10 (Entry)$69,138
P25$80,871
Median$83,514
P75$89,348
P90 (Top)$101,102

Cost-of-Living Adjusted Comparison

After cost-of-living adjustment, San Francisco ($86,224 effective) pays 12.33% more than Santa Maria ($76,761 effective).

San Francisco
Nominal: $99,686
CoL Index: 115.613
Adjusted: $86,224
Santa Maria
Nominal: $83,514
CoL Index: 108.798
Adjusted: $76,761

Cost-of-living adjustment: salary × (100 / CoL index). Index of 100 = national average.

Which City Is Right for You?

Choose San Francisco if…

  • Higher median salary ($99,686/year)
  • Better top-earner potential ($115,340)
  • Larger job market (8,800 employed)
  • Better purchasing power (CoL-adjusted: $86,224)
  • You prefer the California area and lifestyle

Choose Santa Maria if…

  • You prefer the California area and lifestyle

Historical Salary Growth Comparison

Based on BLS OEWS metropolitan area data, licensed practical nurse salaries in San Francisco grew 39.7% from 2019 to 2025, compared to 32.6% growth in Santa Maria over the same period.

San Francisco, CA

+39.7%

$67,520 (2019) → $94,310 (2025)

Santa Maria, CA

+32.6%

$59,580 (2019) → $79,010 (2025)

View Full Salary Data

Frequently Asked Questions

Which city pays licensed practical nurses more: San Francisco or Santa Maria?

San Francisco has a higher median licensed practical nurse salary at $99,686/year, compared to Santa Maria at $83,514/year — a difference of $16,172 (19.36%).

What is the hourly rate difference between San Francisco and Santa Maria?

San Francisco licensed practical nurses earn $47.92/hr while Santa Maria hygienists earn $40.16/hr (2026 est.).

Should I relocate from San Francisco to Santa Maria as a licensed practical nurse?

Consider more than just salary when comparing San Francisco and Santa Maria. Factor in cost of living (CoL-adjusted: San Francisco = $86,224, Santa Maria = $76,761), job availability (8,800 vs 650 employed), commute, and career growth potential.

What do entry-level licensed practical nurses earn in San Francisco vs Santa Maria?

Entry-level (10th percentile) licensed practical nurses earn $80,226 in San Francisco and $69,138 in Santa Maria. The San Francisco area offers higher starting salaries.

Related Comparisons

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Written by Aisha Malik, LPN

Career Analyst

Aisha has 10 years of experience as a licensed practical nurse. She specializes in pediatric nursing. Aisha has worked in various outpatient clinics.

Clinically reviewed by Daniel Thompson, LPNData verified by Maria Gonzalez, LPN

Methodology & Data Source

All salary figures are 2026 projections based on BLS OEWS May 2025 data. A 5.70% CAGR (derived from 6-year national BLS trends) was applied to estimate current compensation. Cost-of-living adjustments use BEA Regional Price Parity data. Actual salaries vary by employer, certifications, and experience.

Data Sources & Methodology

Source: BLS, OEWS , released .

Compiled and verified by Aisha Malik, LPN, a licensed licensed practical nurse with 10+ years of clinical experience. · View source data at BLS.gov