LPN Salary

St. Charles vs St. Louis: Licensed Practical Nurse Salary (2026)

Compare licensed practical nurse salaries between St. Charles, MO and St. Louis, MO. All figures are 2026 estimates projected from BLS 2025 data.

St. Charles, MO
$65,236
$31.36/hr
St. Louis, MO
$68,832
$33.09/hr

Side-by-Side Comparison

MetricSt. Charles, MOSt. Louis, MO
Median Salary$65,236$68,832
Hourly Rate$31.36$33.09
Entry Level (P10)$50,248$59,837
25th Percentile$59,174$64,488
75th Percentile$76,212$80,512
Top Earner (P90)$82,368$84,127
Total Employed165,180
Side-by-side bar chart comparing St. Charles ($65,236) and St. Louis ($68,832) licensed practical nurse salaries.St. CharlesSt. LouisMedian Salary$65,236$68,832Entry Level (P10)$50,248$59,837Top Earner (P90)$82,368$84,127US Median $68,071

Verdict

St. Louis, MO offers better overall compensation for licensed practical nurses, winning 4 out of 4 metrics compared to St. Charles.

The salary gap between St. Charles and St. Louis is $3,596 (5.51%). St. Louis's median is +1.12% compared to the US national median of $68,071.

Salary Range Comparison

The full salary range (10th to 90th percentile) in St. Charles spans $32,120,St. Louis spans $24,290. St. Charles has a wider pay range, meaning more potential for high earners but also more variation.

St. Charles
P10 (Entry)$50,248
P25$59,174
Median$65,236
P75$76,212
P90 (Top)$82,368
St. Louis
P10 (Entry)$59,837
P25$64,488
Median$68,832
P75$80,512
P90 (Top)$84,127

Cost-of-Living Adjusted Comparison

After cost-of-living adjustment, St. Charles ($72,808 effective) pays 0.58% more than St. Louis ($72,388 effective).

St. Charles
Nominal: $65,236
CoL Index: 89.6
Adjusted: $72,808
St. Louis
Nominal: $68,832
CoL Index: 95.088
Adjusted: $72,388

Cost-of-living adjustment: salary × (100 / CoL index). Index of 100 = national average.

Which City Is Right for You?

Choose St. Charles if…

  • Better purchasing power (CoL-adjusted: $72,808)
  • You prefer the Missouri area and lifestyle

Choose St. Louis if…

  • Higher median salary ($68,832/year)
  • Better top-earner potential ($84,127)
  • Larger job market (5,180 employed)
  • You prefer the Missouri area and lifestyle

Historical Salary Growth Comparison

Based on BLS OEWS metropolitan area data, licensed practical nurse salaries in St. Charles grew 31.0% from 2024 to 2025, compared to 39.8% growth in St. Louis over the same period.

St. Charles, MO

+31.0%

$47,113 (2024) → $61,718 (2025)

St. Louis, MO

+39.8%

$46,590 (2019) → $65,120 (2025)

View Full Salary Data

Frequently Asked Questions

Which city pays licensed practical nurses more: St. Charles or St. Louis?

St. Louis has a higher median licensed practical nurse salary at $68,832/year, compared to St. Charles at $65,236/year — a difference of $3,596 (5.51%).

What is the hourly rate difference between St. Charles and St. Louis?

St. Charles licensed practical nurses earn $31.36/hr while St. Louis hygienists earn $33.09/hr (2026 est.).

Should I relocate from St. Charles to St. Louis as a licensed practical nurse?

Consider more than just salary when comparing St. Charles and St. Louis. Factor in cost of living (CoL-adjusted: St. Charles = $72,808, St. Louis = $72,388), job availability (16 vs 5,180 employed), commute, and career growth potential.

What do entry-level licensed practical nurses earn in St. Charles vs St. Louis?

Entry-level (10th percentile) licensed practical nurses earn $50,248 in St. Charles and $59,837 in St. Louis. The St. Louis area offers higher starting salaries.

Related Comparisons

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Written by Aisha Malik, LPN

Career Analyst

Aisha has 10 years of experience as a licensed practical nurse. She specializes in pediatric nursing. Aisha has worked in various outpatient clinics.

Clinically reviewed by Daniel Thompson, LPNData verified by Maria Gonzalez, LPN

Methodology & Data Source

All salary figures are 2026 projections based on BLS OEWS May 2025 data. A 5.70% CAGR (derived from 6-year national BLS trends) was applied to estimate current compensation. Cost-of-living adjustments use BEA Regional Price Parity data. Actual salaries vary by employer, certifications, and experience.

Data Sources & Methodology

Source: BLS, OEWS , released .

Compiled and verified by Aisha Malik, LPN, a licensed licensed practical nurse with 10+ years of clinical experience. · View source data at BLS.gov