LPN Salary

St. Louis vs Jefferson City: Licensed Practical Nurse Salary (2026)

Compare licensed practical nurse salaries between St. Louis, MO and Jefferson City, MO. All figures are 2026 estimates projected from BLS 2025 data.

St. Louis, MO
$68,832
$33.09/hr
Jefferson City, MO
$63,779
$30.66/hr

Side-by-Side Comparison

MetricSt. Louis, MOJefferson City, MO
Median Salary$68,832$63,779
Hourly Rate$33.09$30.66
Entry Level (P10)$59,837$50,218
25th Percentile$64,488$53,653
75th Percentile$80,512$71,823
Top Earner (P90)$84,127$80,448
Total Employed5,180350
Side-by-side bar chart comparing St. Louis ($68,832) and Jefferson City ($63,779) licensed practical nurse salaries.St. LouisJefferson CityMedian Salary$68,832$63,779Entry Level (P10)$59,837$50,218Top Earner (P90)$84,127$80,448US Median $68,071

Verdict

St. Louis, MO offers better overall compensation for licensed practical nurses, winning 4 out of 4 metrics compared to Jefferson City.

The salary gap between St. Louis and Jefferson City is $5,053 (7.92%). St. Louis's median is +1.12% compared to the US national median of $68,071.

Salary Range Comparison

The full salary range (10th to 90th percentile) in St. Louis spans $24,290,Jefferson City spans $30,230. Jefferson City has a wider pay range, suggesting more variation in pay between entry-level and experienced licensed practical nurses.

St. Louis
P10 (Entry)$59,837
P25$64,488
Median$68,832
P75$80,512
P90 (Top)$84,127
Jefferson City
P10 (Entry)$50,218
P25$53,653
Median$63,779
P75$71,823
P90 (Top)$80,448

Cost-of-Living Adjusted Comparison

After cost-of-living adjustment, Jefferson City ($72,497 effective) pays 0.15% more than St. Louis ($72,388 effective).

St. Louis
Nominal: $68,832
CoL Index: 95.088
Adjusted: $72,388
Jefferson City
Nominal: $63,779
CoL Index: 87.975
Adjusted: $72,497

Cost-of-living adjustment: salary × (100 / CoL index). Index of 100 = national average.

Which City Is Right for You?

Choose St. Louis if…

  • Higher median salary ($68,832/year)
  • Better top-earner potential ($84,127)
  • Larger job market (5,180 employed)
  • You prefer the Missouri area and lifestyle

Choose Jefferson City if…

  • Better purchasing power (CoL-adjusted: $72,497)
  • You prefer the Missouri area and lifestyle

Historical Salary Growth Comparison

Based on BLS OEWS metropolitan area data, licensed practical nurse salaries in St. Louis grew 39.8% from 2019 to 2025, compared to 58.4% growth in Jefferson City over the same period.

St. Louis, MO

+39.8%

$46,590 (2019) → $65,120 (2025)

Jefferson City, MO

+58.4%

$38,090 (2019) → $60,340 (2025)

View Full Salary Data

Frequently Asked Questions

Which city pays licensed practical nurses more: St. Louis or Jefferson City?

St. Louis has a higher median licensed practical nurse salary at $68,832/year, compared to Jefferson City at $63,779/year — a difference of $5,053 (7.92%).

What is the hourly rate difference between St. Louis and Jefferson City?

St. Louis licensed practical nurses earn $33.09/hr while Jefferson City hygienists earn $30.66/hr (2026 est.).

Should I relocate from St. Louis to Jefferson City as a licensed practical nurse?

Consider more than just salary when comparing St. Louis and Jefferson City. Factor in cost of living (CoL-adjusted: St. Louis = $72,388, Jefferson City = $72,497), job availability (5,180 vs 350 employed), commute, and career growth potential.

What do entry-level licensed practical nurses earn in St. Louis vs Jefferson City?

Entry-level (10th percentile) licensed practical nurses earn $59,837 in St. Louis and $50,218 in Jefferson City. The St. Louis area offers higher starting salaries.

Related Comparisons

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Written by Aisha Malik, LPN

Career Analyst

Aisha has 10 years of experience as a licensed practical nurse. She specializes in pediatric nursing. Aisha has worked in various outpatient clinics.

Clinically reviewed by Daniel Thompson, LPNData verified by Maria Gonzalez, LPN

Methodology & Data Source

All salary figures are 2026 projections based on BLS OEWS May 2025 data. A 5.70% CAGR (derived from 6-year national BLS trends) was applied to estimate current compensation. Cost-of-living adjustments use BEA Regional Price Parity data. Actual salaries vary by employer, certifications, and experience.

Data Sources & Methodology

Source: BLS, OEWS , released .

Compiled and verified by Aisha Malik, LPN, a licensed licensed practical nurse with 10+ years of clinical experience. · View source data at BLS.gov