LPN Salary

O'Fallon vs St. Louis: Licensed Practical Nurse Salary (2026)

Compare licensed practical nurse salaries between O'Fallon, MO and St. Louis, MO. All figures are 2026 estimates projected from BLS 2025 data.

O'Fallon, MO
$64,479
$31.00/hr
St. Louis, MO
$68,832
$33.09/hr

Side-by-Side Comparison

MetricO'Fallon, MOSt. Louis, MO
Median Salary$64,479$68,832
Hourly Rate$31.00$33.09
Entry Level (P10)$48,443$59,837
25th Percentile$57,572$64,488
75th Percentile$75,823$80,512
Top Earner (P90)$86,334$84,127
Total Employed225,180
Side-by-side bar chart comparing O'Fallon ($64,479) and St. Louis ($68,832) licensed practical nurse salaries.O'FallonSt. LouisMedian Salary$64,479$68,832Entry Level (P10)$48,443$59,837Top Earner (P90)$86,334$84,127US Median $68,071

Verdict

St. Louis, MO offers better overall compensation for licensed practical nurses, winning 3 out of 4 metrics compared to O'Fallon.

The salary gap between O'Fallon and St. Louis is $4,353 (6.75%). St. Louis's median is +1.12% compared to the US national median of $68,071.

Salary Range Comparison

The full salary range (10th to 90th percentile) in O'Fallon spans $37,891,St. Louis spans $24,290. O'Fallon has a wider pay range, meaning more potential for high earners but also more variation.

O'Fallon
P10 (Entry)$48,443
P25$57,572
Median$64,479
P75$75,823
P90 (Top)$86,334
St. Louis
P10 (Entry)$59,837
P25$64,488
Median$68,832
P75$80,512
P90 (Top)$84,127

Cost-of-Living Adjusted Comparison

After cost-of-living adjustment, St. Louis ($72,388 effective) pays 0.59% more than O'Fallon ($71,963 effective).

O'Fallon
Nominal: $64,479
CoL Index: 89.6
Adjusted: $71,963
St. Louis
Nominal: $68,832
CoL Index: 95.088
Adjusted: $72,388

Cost-of-living adjustment: salary × (100 / CoL index). Index of 100 = national average.

Which City Is Right for You?

Choose O'Fallon if…

  • Better top-earner potential ($86,334)
  • You prefer the Missouri area and lifestyle

Choose St. Louis if…

  • Higher median salary ($68,832/year)
  • Larger job market (5,180 employed)
  • Better purchasing power (CoL-adjusted: $72,388)
  • You prefer the Missouri area and lifestyle

Historical Salary Growth Comparison

Based on BLS OEWS metropolitan area data, licensed practical nurse salaries in O'Fallon grew 31.0% from 2024 to 2025, compared to 39.8% growth in St. Louis over the same period.

O'Fallon, MO

+31.0%

$46,567 (2024) → $61,002 (2025)

St. Louis, MO

+39.8%

$46,590 (2019) → $65,120 (2025)

View Full Salary Data

Frequently Asked Questions

Which city pays licensed practical nurses more: O'Fallon or St. Louis?

St. Louis has a higher median licensed practical nurse salary at $68,832/year, compared to O'Fallon at $64,479/year — a difference of $4,353 (6.75%).

What is the hourly rate difference between O'Fallon and St. Louis?

O'Fallon licensed practical nurses earn $31.00/hr while St. Louis hygienists earn $33.09/hr (2026 est.).

Should I relocate from O'Fallon to St. Louis as a licensed practical nurse?

Consider more than just salary when comparing O'Fallon and St. Louis. Factor in cost of living (CoL-adjusted: O'Fallon = $71,963, St. Louis = $72,388), job availability (22 vs 5,180 employed), commute, and career growth potential.

What do entry-level licensed practical nurses earn in O'Fallon vs St. Louis?

Entry-level (10th percentile) licensed practical nurses earn $48,443 in O'Fallon and $59,837 in St. Louis. The St. Louis area offers higher starting salaries.

Related Comparisons

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Written by Aisha Malik, LPN

Career Analyst

Aisha has 10 years of experience as a licensed practical nurse. She specializes in pediatric nursing. Aisha has worked in various outpatient clinics.

Clinically reviewed by Daniel Thompson, LPNData verified by Maria Gonzalez, LPN

Methodology & Data Source

All salary figures are 2026 projections based on BLS OEWS May 2025 data. A 5.70% CAGR (derived from 6-year national BLS trends) was applied to estimate current compensation. Cost-of-living adjustments use BEA Regional Price Parity data. Actual salaries vary by employer, certifications, and experience.

Data Sources & Methodology

Source: BLS, OEWS , released .

Compiled and verified by Aisha Malik, LPN, a licensed licensed practical nurse with 10+ years of clinical experience. · View source data at BLS.gov