Licensed Practical Nurse Salary in O'Fallon, MO: $64,479 (2026)
Quick Answer:A full-time licensed practical nurse in O'Fallon, MO earns a median $64,479/year (โ $31.00/hour) in nominal terms for 2026 โ projected from BLS OEWS 2025 (SOC 29-2061). Once you factor in O'Fallon's price level (10% below national, BEA RPP 89.6), that paycheck buys what $71,963 would nationally. Nominal pay sits 0.1% below the Missouri state average.
Based on BLS state-level estimates ยท View source

In O'Fallon, Missouri, the projected median salary for licensed practical nurses is $64,479 in 2026, which is slightly below the national median of $68,071. The local pay range for this role extends from $48,443 at the 10th percentile to $86,334 at the 90th percentile, reflecting the variance in workplace settings and experience levels. These estimates, based on 2025 BLS data projected to 2026, account for regional cost adjustments, giving potential LPNs a clearer picture of expected compensation in the local market. Factors such as shift differentials and weekend premiums play a significant role in stabilizing compensation for those in long-term care, driving competitive pay strategies for licensed practical nursing professionals in the area.
About the O'Fallon Market
Salary estimated from Missouri average ($52,000) adjusted for local cost of living.
Salary Breakdown
| Percentile | Annual | Hourly |
|---|---|---|
| Entry Level (P10) | $48,443 | $23.29 |
| Lower Range (P25) | $57,572 | $27.68 |
| Median (P50)(typical) | $64,479 | $31.00 |
| Upper Range (P75) | $75,823 | $36.46 |
| Top Earners (P90) | $86,334 | $41.51 |
Median Salary Position
5.28% below the national average
2026 Salary Percentile Distribution in O'Fallon
In O'Fallon, MO, the licensed practical nurse salary spread from the 10th to 90th percentile is $37,891 (2026 est.). At $64,479, the local median is 5.28% below the national median of $68,071.
Salary Calculator
At 40 hours/week in O'Fallon: You'd be in the lower-middle range
How O'Fallon Licensed Practical Nurse Pay Compares
O'Fallon median: $64,479/year (2026)
| Compared To | Median Salary | O'Fallon Pays |
|---|---|---|
| Missouri Average | $64,544 | -0.10% less |
| National Average | $68,071 | -5.28% less |
Licensed Practical Nurses in O'Fallon, MO earn a median of $64,479 per year (2026 est.), which is 5.28% lower than the national median of $68,071 and 0.10% below the Missouri state average of $64,544.
Cost-of-Living Adjusted Salary
O'Fallon has a cost of living 10.40% below the national average, meaning your salary goes further here.
Adjusted salary = nominal ร (100 / CoL index). CoL index: 100 = national average.
O'Fallon, MO has a cost-of-living index of 89.6 (below the national average of 100). A licensed practical nurse earning $64,479 nominally has purchasing power equivalent to $71,963 in an average-cost city โ an effective 11.61% boost.
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2019 BLS Actual
$44,975
2025 BLS Actual
$61,002
2026 Current Est.
$64,479
2019โ2027 Growth
+51.5%
Salary Trajectory for Licensed Practical Nurses in O'Fallon (2019โ2027)
2019โ2025: actual BLS OEWS data for this metro area. 2026+: CAGR 5.70% projection.
| Year | Annual Salary | Status |
|---|---|---|
| 2019 | $44,975 | Actual |
| 2020 | $46,244 | Actual |
| 2021 | $45,534 | Actual |
| 2022 | $51,738 | Actual |
| 2023 | $56,578 | Actual |
| 2024 | $46,567 | Actual |
| 2025 | $61,002 | Actual |
| 2026(current) | $64,479 | Estimated |
| 2027 | $68,154 | Projected |
Based on 7 years of BLS OEWS data for the O'Fallon metropolitan area, the median licensed practical nurse salary grew 35.6% from $44,975 (2019) to $61,002 (2025). At a 5.70% compound annual growth rate, salaries are projected to reach $68,154 by 2027 โ a total increase of $23,179 (51.54%) from 2019.
Note: Historical values (2019โ2025) are actual BLS OEWS figures for the O'Fallon metropolitan area, sourced from annual Occupational Employment and Wage Statistics surveys. 2026โ2026 figures are current estimates, and 2027 values are projections, calculated using a 5.70% CAGR derived from 7-year BLS historical data. Actual salaries may vary based on employer, experience, certifications, and local market conditions.
Salary by Experience Level
| Experience | Estimated Salary Range |
|---|---|
| 0-2 years (New Graduate) | $48,443 โ $57,572 |
| 3-5 years (Mid Career) | $57,572 โ $64,479 |
| 5+ years (Experienced) | $64,479 โ $75,823 |
| 10+ years (Top Earner) | $75,823 โ $86,334 |
LPN salary ranges estimated from BLS percentile data. Individual licensed practical nurse compensation varies by employer, certifications, and specialization.
Licensed Practical Nurse Job Market in O'Fallon
The job market for licensed practical nurses in O'Fallon consists of around 22 practitioners, indicating a modest workforce in a market characterized by a lower cost-of-living index of 89.6. This presents an opportunity for LPNs considering how far their earnings can stretch in terms of purchasing power. Skilled nursing facilities typically offer the highest wages, followed by home health agencies, while physician offices offer the lowest. The disparity in pay can be attributed to various factors such as the nature of the work environment, shift differentials, and various stipends for advanced certifications like IV therapy. To maximize earnings within this competitive landscape, LPNs should consider seeking positions in long-term care settings where premiums for weekends and holidays are common, and explore pathways for professional advancement through LPN-to-RN bridge programs, increasing both responsibilities and salary potential.
More salary data for O'Fallon, MO:
Frequently Asked Questions
How much do licensed practical nurses make in O'Fallon, MO in 2026?
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Can licensed practical nurses make $100K in O'Fallon?
What is the cost-of-living adjusted licensed practical nurse salary in O'Fallon?
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Written by Aisha Malik, LPN
Career Analyst
Aisha has 10 years of experience as a licensed practical nurse. She specializes in pediatric nursing. Aisha has worked in various outpatient clinics.
Methodology & Data Source
Salary figures on this page are 2026 projections based on the Bureau of Labor Statistics Occupational Employment and Wage Statistics (OEWS) survey, May 2026 release. The BLS reported a median annual salary of $61,002 for licensed practical nursesin the O'Fallon metropolitan area. A 5.70% compound annual growth rate (CAGR), calculated from 6-year national BLS wage trends, was applied to project current 2026 compensation. Percentile ranges (P10โP90) represent the full salary distribution across experience levels and practice settings in this market.
Data Sources & Methodology
Salary data for O'Fallon is estimated from official BLS state-level occupational wage data (2025), adjusted for regional cost-of-living differences using BEA RPP (Regional Price Parities).
2026 figures are projected from 2025 BLS data using a compound annual growth rate (CAGR) of 5.70%, derived from historical BLS wage trends for licensed practical nurses (SOC 29-2061).
Compiled and verified by Aisha Malik, LPN, a licensed licensed practical nurse with 10+ years of clinical experience. ยท View source data at BLS.gov